Due to their large size, predatory prowess and indiscernible palette, tiger sharks have very few, if any, natural predators. More dangerous to the population of tiger sharks are humans, who hunt the shark for its fins, teeth, skin and flesh. Tiger sharks also contain high amounts of vitamin A in their livers, leading to their capture for the production of vitamin oil.
Sharks are typically at the top of the food chain in their habitats. Tiger sharks help to keep populations of smaller fish (their prey) under control, preventing overpopulation and the imbalance of the oceanic ecosystem. Some coastal areas enforce regulations regarding tiger shark fishing practices to prevent the extinction of the species.